首页> 外国专利> Process for preparing a pharmaceutical composition for use as an anti-arrhythmia drug with a controlled beta-adrenergic block, pharmaceutical composition, oral and parenteral preparation for the treatment of heart disease in mammals, and method of treatment for them

Process for preparing a pharmaceutical composition for use as an anti-arrhythmia drug with a controlled beta-adrenergic block, pharmaceutical composition, oral and parenteral preparation for the treatment of heart disease in mammals, and method of treatment for them

机译:具有受控的β-肾上腺素阻滞剂的用作抗心律不齐药物的药物组合物的制备方法,药物组合物,用于治疗哺乳动物心脏病的口服和肠胃外制剂及其治疗方法

摘要

"PHARMACEUTICAL COMPOSITION FOR USE AS AN ANTIARRHYTHMIC MEDICINE WITH A CONTROLLED ADRENERGIC BETA BLOCK, ORAL AND PARENTERAL PREPARATION FOR TREATING MAMMALIAN HEART DISEASES AND TREATMENT METHOD FOR THE SAME". The invention describes a safer antiarrhythmic drug with a controlled beta-adrenergic activity that comprises a combination of sotalol dextro- and rotating levo-isomers as active ingredients in which the ratio of said dextro- and levo-isomers is 1, 5: 1 to 3.05: 1, pharmaceutical compositions with this combination as active ingredients and their preparation and use of this combination in the treatment of heart disease in mammals, including human beings.
机译:“药物组合物用作抗心律失常药物,具有受控的肾上腺β-受体阻滞剂,口服和肠旁准备,可治疗哺乳动物的心脏疾病及其治疗方法”。本发明描述了一种具有受控的β-肾上腺素能活性的更安全的抗心律不齐药物,其包含索他洛尔右旋和左旋异构体的组合作为活性成分,其中所述右旋和左旋异构体的比例为1、5:1至3.05 :1,以该组合为有效成分的药物组合物,及其在哺乳动物(包括人)的心脏病治疗中的制备和使用。

著录项

  • 公开/公告号BR9915951A

    专利类型

  • 公开/公告日2001-08-21

    原文格式PDF

  • 申请/专利权人 TORRENT PHARMACEUTICALS LTD.;

    申请/专利号BR19999915951

  • 发明设计人 ALANGUDI SANKARANARAYANAN;

    申请日1999-02-22

  • 分类号A61K31/18;

  • 国家 BR

  • 入库时间 2022-08-22 01:25:54

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