Famaceuticas compositions containing an Association tagonista Selective receptors of arginine vasopressin V1a and v2 receptor antagonist Selective for arginine -Opresina

摘要

The present invention relates to pharmaceutical compositions containing in association (2S) -1- [2R, 3S) -5-chloro-3- (2-chlorophenyl) -1- (3,4-dimethoxy benzenesulfonyl) -3-hydroxy -2,3-dihydro-1 H-indole-2-carbonyl] pyrrolidine-2-carboxamide, a selective antagonist of arginine vasopressin V1a receptors, with 1- [4- (N-tert-butylcarbamoyl) -2 -methoxybenzenesulfonyl] -5-ethoxy-3-spiro [4- (2-mofolinoeti loxi) cyclohexane] indole-2 -Ona, equatorial isohorne, or one of its salts,The invention refers to the use of these compounds in the production of drugs for the treatment of all diseases related to vascular compression arginin or V2 receptor, and the treatment of these diseases is based on selective antagonism to V2 receptor.