USE OF AMINO-INDANONE INHIBITORS OF TRANSCRIPTION FACTOR NF-KB FOR PRODUCING PHARMACEUTICAL COMPOSITIONS

摘要

The present invention relates to NF-κB transcription factor inhibitors, in particular to amino-indanone inhibitors of formula I, wherein R1 is aryl; R 2 is hydrogen, C 1-6 alkyl or aryl; R3 is C1-6 alkyl or C3-8cycloalkyl; and R2 and R3 may be linked to form a 5-7-atom heterocyclic ring, the ring atoms of which are selected from the group consisting of carbon, nitrogen, oxygen and sulfur. HE