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SOLID PHASE SYNTHESIS OF COMPOUNDS BY CARBON-CARBON BOND FORMING MITSUNOBU REACTIONS
SOLID PHASE SYNTHESIS OF COMPOUNDS BY CARBON-CARBON BOND FORMING MITSUNOBU REACTIONS
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机译:碳-碳键形成MITSUNOBU反应固相合成化合物
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摘要
Processes are provided for the Mitsunobu alkylation reaction of carbon-carbon bond formation between a solid support reagent and a reagent in solution. The resulting novel products can be prepared as a combinatorial library by high-throughput, parallel synthesis under robotic automation. Cleaved or support-bound products are useful precursors to biologically active compounds.
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