首页> 外国专利> Carbamate derivatives of 4-amino-3-isoxazolidinone, 3-amino-1-hydroxypyrrolidin-2-one and 1-amino-1-cyclopropanecarboxylic acid homologs, methods for their preparation and their use as medicaments

Carbamate derivatives of 4-amino-3-isoxazolidinone, 3-amino-1-hydroxypyrrolidin-2-one and 1-amino-1-cyclopropanecarboxylic acid homologs, methods for their preparation and their use as medicaments

机译:4-氨基-3-异恶唑烷酮,3-氨基-1-羟基吡咯烷酮-2-酮和1-氨基-1-环丙烷羧酸同系物的氨基甲酸酯衍生物,其制备方法和用作药物

摘要

The present invention provides carbamate derivatives of 4-amino-3-isoxazolidinone, 3-amino-1-hydroxypyrrolidin-2-one and 1-amino-1-cyclopropanecarboxylic acid homologue of general formula (I). And their preparation as a medicament.;Wherein R 1 is;R 2 is;or;to be.;The compounds are useful for alleviating various memory dysfunctions characterized by cholinergic deficiencies such as Alzheimer's disease.
机译:本发明提供了通式(I)的4-氨基-3-异恶唑烷酮,3-氨基-1-羟基吡咯烷酮-2-酮和1-氨基-1-环丙烷羧酸同系物的氨基甲酸酯衍生物。其中R 1 为; R 2 为;或;待定;所述化合物可用于减轻以胆碱能缺乏为特征的各种记忆功能障碍例如老年痴呆症。

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