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unsaturated in 4 - position substituted 6 - tert butyl - 1 - dimethylindan derivatives and their use in human and veterinary medicine
unsaturated in 4 - position substituted 6 - tert butyl - 1 - dimethylindan derivatives and their use in human and veterinary medicine
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机译:4位取代的6-叔丁基1-二甲基茚满衍生物中的不饱和及其在人类和兽药中的应用
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摘要
4-Unsaturated-6-tert. butyl-1,1-dimethyl indane derivatives (I). 4-Unsaturated-6-tert. butyl 1,1-dimethyl indane derivatives of formula (I), their salts, and geometric and optical isomers, are new. X = a group of formula (a) and Y = a group of formula (b); or X = C(=CH2) and Y = (b), pyrid-di-yl, or a group of formula (e) or (f); Z = O, S, or =N-R3; R1 = Me, (CH2)p-OR4, (CH2)p-COR5, or S(O)t-R6; p = 0-3; t = 0-2; R2 = H or lower alkyl; R3 = H, lower alkoxy, or COR7; R4 = H, lower alkyl, COR7, aryl, aralkyl, mono- or poly-hydroxyalkyl, or a polyether; R5 = H, lower alkyl, OR8, or -N(R')(R"); R6 = H or lower alkyl; R7 = lower alkyl; R8 = H, alkyl, alkenyl, alkynyl, aryl, aralkyl, mono- or poly-hydroxyalkyl, a sugar residue or an amino acid residue;R', R" = H, lower alkyl, COR7, aryl, a sugar residue or an amino acid residue; or NR'R" = a heterocycle.
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