19-nor steroids having a thiocarbonated chain in position 11beta, their preparation process and the intermediates of this process, and the intermediates of this process, their use as medicaments and compositions

摘要

Compounds of formula (I), wherein R₁₇ and R₁₇ are such that: either R₁₇ and R₁₇ together form ketone, hydrazono, oxime or methylene, or R₁₇ is hydroxyl, hydroxymethyl or acyloxy and R₁₇ is hydrogen, alkyl or optionally substitued alkenyl or alkynyl; R₃ is hydrogen or alkyl; R₁₆ is hydrogen, halogen or alkyl; m is 0, 1 or 2; X, Y and Z are such that: X is methylene, arylene or arylenoxy bonded to the steroid by a carbon atom; Y is a saturated or unsaturated straight or branched aliphatic chain which is optionally interrupted by oxygen; and Z is aryl, arylalkyl or straight or branched alkyl; addition salts thereof, a preparation method therefor, medicinal uses thereof, compositions containing said compounds, and resulting novel intermediates.