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Screening system good sensitivity for envelope-defective recombinant virus.

机译:筛选系统对包膜缺陷重组病毒具有良好的敏感性。

摘要

(57) an indicator cell line complements in trans SUMMARY envelope defective recombinant viruses can be used to amplify the virus. For example, by the cell that contains the viral envelope gene, exposing the enveloped defective retrovirus, there is provided a method of amplifying a retrovirus, viral envelope encoded by the gene complements retrovirus, the invention relates to a method . The method of the present invention also relates to a method of virus envelope, is expressed on the surface of viral particles produced by the cells. The methods of the present invention is also directed to methods of viral envelope is expressed by the cell.
机译:(57)在反式发明概述中有缺陷的重组缺陷病毒的指示细胞系可用于扩增病毒。例如,通过包含病毒包膜基因的细胞暴露被包膜的逆转录病毒,提供了一种扩增逆转录病毒的方法,该基因编码的病毒包膜补充了逆转录病毒,本发明涉及一种方法。本发明的方法还涉及病毒包膜的方法,在细胞产生的病毒颗粒表面表达。本发明的方法还涉及由细胞表达病毒包膜的方法。

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