首页> 外国专利> PROCESS FOR THE SYNTHESIS OF NUCLEIC ACIDS ON A SOLID SUPPORT AND COMPOUNDS WHICH ARE USEFUL IN PARTICULAR AS SOLID SUPPORTS IN THE SAID PROCESS

PROCESS FOR THE SYNTHESIS OF NUCLEIC ACIDS ON A SOLID SUPPORT AND COMPOUNDS WHICH ARE USEFUL IN PARTICULAR AS SOLID SUPPORTS IN THE SAID PROCESS

机译:在固体支持物上合成核酸的过程以及特别适用于上述过程中固体支持物的化合物

摘要

The object of the present invention is a process for synthesizing solid phase nucleic acids, characterized in that a mineral or organic polymer, bound by a bivalent hydrocarbon radical to an epoxy or glycol-type group, is used as a solid support, said epoxy or glycol-type group comprising two adjacent saturated carbon atoms on which an OH and a nucleophilic group are substituted. The present invention also pertains to compounds containing an epoxy or glycol-type group as defined above, useful for example as a solid support in a process for solid support nucleic acid synthesis.
机译:本发明的目的是合成固相核酸的方法,其特征在于通过二价烃基结合至环氧基或二醇型基团的矿物或有机聚合物用作固相支持物,所述环氧化物或包含两个相邻的饱和碳原子的二元醇型基团,OH和亲核基团被其取代。本发明还涉及含有如上定义的环氧基或二醇型基团的化合物,其例如在固体支持物核酸合成方法中用作固体支持物。

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