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Expression-cloning method for identifying target proteins for eukaryotic tyrosine kinases and novel target proteins
Expression-cloning method for identifying target proteins for eukaryotic tyrosine kinases and novel target proteins
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机译:真核酪氨酸激酶靶蛋白和新型靶蛋白的表达克隆方法
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摘要
The present invention relates to a novel method, based on direct expression cloning, for identifying target proteins capable of binding to and/or serving as substrates for receptor or cytoplasmic tyrosine kinases. The present invention also relates to novel proteins identified using this method, and to methods for identifying compounds that disrupt the interaction of such novel proteins with the receptor or cytoplasmic tyrosine kinases.
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