;wherein R1 and R2 are selected from the group consisting of a hydrogen, a C1-11 alkyl group; R3 and R4 are selected from the group consisting of a hydrogen, a C1-11 alkyl group, a C3-10 aryl group, a C1-2CO2H carboxyalkyl group; and X represents hydrogen or a lower alkoxy group having 1 to 6 carbons."/> Substituted 1,2,4-trioxanes as antimalarial agents and a process of producing the substituted 1,2,4-trioxanes
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Substituted 1,2,4-trioxanes as antimalarial agents and a process of producing the substituted 1,2,4-trioxanes

机译:取代的1,2,4-三恶烷类化合物作为抗疟药以及生产取代的1,2,4-三恶烷类化合物的方法

摘要

The present invention relates to novel substituted 1,2,4-trioxanes that are useful as anti-malarial agents, and have a general formula 1, ;wherein R1 and R2 are selected from the group consisting of a hydrogen, a C1-11 alkyl group; R3 and R4 are selected from the group consisting of a hydrogen, a C1-11 alkyl group, a C3-10 aryl group, a C1-2CO2H carboxyalkyl group; and X represents hydrogen or a lower alkoxy group having 1 to 6 carbons.
机译:本发明涉及用作抗疟剂并具有通式1的新型取代的1,2,4-三恶烷。<化学编号=“ CHEM-US-00001”> <图像文件=“ US06316493-20011113 -C00001.GIF“ id =” EMI-C00001“ imgContent =” undefined“ imgFormat =” GIF“ /> ;其中R 1 和R 2 选自:氢,C 1-11 烷基; R 3 和R 4 选自氢,C 1-11 烷基,C 3 -10 芳基,C 1-2 CO 2 H羧基烷基; X表示氢或碳数1〜6的低级烷氧基。

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