Compound, pharmaceutical composition, and methods of treating a cancer patient, inhibiting protein kinases in a patient, inhibiting cyclin-dependent kinases in a patient, and preparing the compound

摘要

"COMPOUND, PHARMACEUTICAL COMPOSITION, AND, METHOD OF TREATING A CANCER PATIENT, INHIBITING PROTEIN KINASES IN A PATIENT, INHIBITING CYCLINE-DEPENDENT KINASES IN A PATIENT, AND COMPOUND PREPARATION". The present invention comprises a pseudopolymorphic hydrochloride form of (-) - cis-2- (2-chloro-phenyl) -5,7-dihydroxy-8- [4R- (3S-hydroxy-1methyl) -piperidine] -4H-1-benzopyran-4-one, a method of its preparation, a pharmaceutical composition and methods of using the pseudopolymorph form.