Derivatives of pyrazoline, the preparation of the same and the application of them as a medicine

摘要

Invention Patent: "PIRAZOLINE DERIVATIVES, PREPARATION OF THE SAME AND THE APPLICATION OF THE SAME AS A MEDICINE". The present invention relates to new pyrazoline derivatives that have the general formula (1), as well as their physiologically acceptable salts, processes in human and veterinary therapy and pharmaceutical compositions containing them. The new compounds of the invention can be used in the pharmaceutical industry as intermediates and in the preparation of medicines. Specifically, they can be used for the preparation of drugs used to treat inflammation and other problems associated with inflammation and other processes mediated by cyclooxygenase-2, for example, arthritis, donor treatment and fever treatment.