Compound, pharmaceutical composition and methods to inhibit tyrosine kinase activity and cell proliferation, differentiation, or mediator release in a patient, and to treat a patient subject to a condition linked to a hyperproliferative disorder and restenosis and inflammation in a patient

摘要

"COMPOUND, PHARMACEUTICAL COMPOSITION AND METHODS TO INHIBIT THYROSINE KINASE ACTIVITY AND CELL PROLIFERATION, DIFFERENTIATION, OR MEDIATOR RELEASE IN A PATIENT, AND TO TREAT A PATIENT SUBJECT TO A PATIENT IN LIABILITY UNDERSTANDING A LACTED PATHOLOGY. This invention relates to quinoline / quinoxaline compounds that inhibit platelet tyrosine kinase-derived growth factor and / or Lck tyrosine kinase, to pharmaceutical compositions comprising these compounds, and to the use of these compounds to treat a patient suffering from, or who is subject to disorders / conditions involving cell differentiation, proliferation, extracellular matrix production or mediator release and / or T cell activation and proliferation.