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Process for producing immunoglobulins from fractions generated by fractionation of human blood plasma
Process for producing immunoglobulins from fractions generated by fractionation of human blood plasma
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机译:从人血浆分级分离产生的级分生产免疫球蛋白的方法
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摘要
Prodn. of a high-titre immunoglobulin (Ig) prepn. comprises: (a) fractionating blood plasma from a plasma pool to separate 1 industrially utilisable polyclonal IgG fraction from a residual fraction; (b) preparing a protein soln. from the protein components of the residual fraction or its subfractions; (c) subjecting the protein soln. to 1 affinity chromatography step in which specific plasma proteins are bound to immobilised ligands of 1 type and the bound proteins are then released, and (d) converting the released proteins into a high-titre Ig prepn.
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