USE OF AMINO-INDANONE INHIBITORS OF TRANSCRIPTION FACTOR NF-KB FOR PRODUCING PHARMACEUTICAL COMPOSITIONS

摘要

The present invention relates to NF-κB transcription factor inhibitors, more particularly to the aminoindanone inhibitors of the formula I wherein R1 is aryl; R 2 is hydrogen, C 1-6 alkyl or aryl; R 3 is C 1 -C 6 alkyl or C 3 -C 8 cycloalkyl: and R 2 and R 3 may be joined together to form a 5 to 7-membered heterocyclic ring selected from carbon, nitrogen, oxygen and sulfur. SHE