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PROCESS OF DECELLULARIZING BIOLOGICAL MATRICES AND ACELLULAR BIOLOGICAL MATRICES USEFUL IN TISSUE ENGINEERING
PROCESS OF DECELLULARIZING BIOLOGICAL MATRICES AND ACELLULAR BIOLOGICAL MATRICES USEFUL IN TISSUE ENGINEERING
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机译:组织工程中常用的脱细胞生物基质和纤维素生物基质的过程
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摘要
A method of decellularizing a biological matrix so as to obtain an acellular biological matrix, as well as clinical uses of the acellular biological matrix are disclosed. The method is effected by (a) obtaining a tissue of interest; (b) treating the tissue of interest with a decellularization solution containing a cell lysis reagent, preferably a combination of a non-ionic detergent with a mild base; (c) removing cell remnants, thereby obtaining the acellular biological matrix; and optionally (d) dehydrating the acellular biological matrix.
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