首页> 外国专利> ISOLATED PEPTIDES WHICH BIND TO HLA-C MOLECULES ANISOLATED PEPTIDES WHICH BIND TO HLA-C MOLECULES AND USES THEREOF D USES THEREOF

ISOLATED PEPTIDES WHICH BIND TO HLA-C MOLECULES ANISOLATED PEPTIDES WHICH BIND TO HLA-C MOLECULES AND USES THEREOF D USES THEREOF

机译:结合至HLA-C分子的分离的肽结合至HLA-C分子的分离的肽及其用途D

摘要

The invention teaches peptide epitopes which bind to HLA-Cw3 and HLA-Cw6 molecules on the surface of cells. The peptides are useful diagnostically an d therapeutically, as are DNA molecules which encode them, and the cytolytic T lymphocytes specific to the HLA/peptide complexes. Also a feature of the invention is a method for identifying relevant molecules such as those described herein, in a system that uses stimulation and restimulation using different viral vectors.
机译:本发明教导了与细胞表面上的HLA-Cw3和HLA-Cw6分子结合的肽表位。该肽和编码它们的DNA分子以及对HLA /肽复合物特异的溶细胞性T淋巴细胞在诊断和治疗上都是有用的。本发明的另一个特征是在使用使用不同病毒载体的刺激和再刺激的系统中鉴定相关分子(例如本文所述的那些分子)的方法。

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