The present invention relates to newly identified CTPase activator proteins (GAPs). The invention also relates to polynucleotides encoding the proteins. The invention further relates to methods using the polypeptides and polynucleotides as a target for diagnosis and treatment in GAP-mediated or related disorders. The invention further relates to drug-screening methods using the polypeptides and polynucleotides to identify agonists and antagonists for diagnosis and treatment. The invention further encompasses agonists and antagonists based on the polypeptides and polynucleotides. The invention further relates to procedures for producing the polypeptides and polynucleotides.
展开▼
