EXPRESSION VECTOR CODING P972 GENE FOR CANCER THERAPY AND ADENOVIRUS PRODUCING THE SAME

摘要

The present invention relates to a vector comprising P972 (also referred to as Gadd45η, CR6 or OIG37) gene known as a gene producing a cell growth-inhibiting protein for the treatment of cancers, an recombinant adenovirus that encodes P972 gene in the cell, a method of producing the above adenovirus and a method for the treatment of cancers by using the above vector or adenovirus. The recombinant adenovirus of the present invention can be used in the treatment of various cancers including cervical cancer, breast cancerand colon cancer.