首页> 外国专利> SYNTHESIS OF (iR/i)-3-(4-BROMOBENZYL)-1-(3,5-DICHLOROPHENYL)-5-IODO-3-METHYL-1-iH/i-IMIDAZO1,2-aIMIDAZOL-2-ONE

SYNTHESIS OF (iR/i)-3-(4-BROMOBENZYL)-1-(3,5-DICHLOROPHENYL)-5-IODO-3-METHYL-1-iH/i-IMIDAZO1,2-aIMIDAZOL-2-ONE

机译:( R )-3-(4-溴苯甲基)-1-(3,5-二氯苯基)-5-碘代-3-甲基-1- H -的合成IMIDAZO [1,2-a] IMIDAZOL-2-ONE

摘要

A novel process for the preparation of (R)-3-(4-Bromobenzyl)-1-(3,5-dichlorophenyl)-5-iodo-3-methyl-1-H-imidazo[1,2-a]imidazol-2-one (1). This compound is useful as an intermediate in the preparation of certain small molecules that are useful in the treatment or prevention of inflammatory and immune cell-mediated diseases. The present invention also relates to certain intermediates used in this novel process.
机译:一种制备(R)-3-(4-溴苄基)-1-(3,5-二氯苯基)-5-碘-3-甲基-1-H-咪唑并[1,2-a]咪唑的新方法-2-一(1)。该化合物可用作制备某些小分子的中间体,这些小分子可用于治疗或预防炎症和免疫细胞介导的疾病。本发明还涉及在该新颖方法中使用的某些中间体。

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