Regulating the respiratory activity of micro-organisms in a fermentation process, esp. an activated sludge process for the purificn. of effluent, comprises rendering part of the nutrient supply (i.e. substrate or effluent contents) inaccessible to the micro-organisms, or degrading part of the supply, by adding substances adsorptive and/or absorptive w.r.t. the nutrient supply, e.g. fine-particle silica derivs., hydrophobic and/or hydrophilic activated carbon, and metal salts.
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