A LINKER SYSTEM FOR THE SYNTHESIS AND SCREENING OF COMBINATORIAL LIBRARIES OF POLYAMINE DERIVATIVES ON WATER COMPATIBLE SUPPORTS

摘要

The invention is directed to resin-conjugated polyamine combinatorial libraries and methods for making and using them, e.g., methods for screening for polyamine binding molecules in biological samples. The invention provides protected benzophenone-substituted resins, and methods for their synthesis. The invention provides hydroxy-triarylmethane-conjugated resins, and methods for their synthesis. The invention provides chlorotriarylmethane resins, and methods for their synthesis. The invention provides resin-conjugated peptide libraries, and methods for their synthesis.