-1 Method for Preparing Bicyclic Compounds and Use of Said Method for Preparing an Interleukin-1SgB Conversion Enzyme ICE Inhibitor

摘要

The present invention relates to compounds of formula (I) from compounds of formula (IA) wherein R = H, alkyl, aryl, aralkyl containing up to 18 carbon atoms, the amine functionality being free or protected, And a method for producing the same. The invention relates to basic media and phosphonic acid derivatives, especially POCl₃Or POBr₃In the presence of a catalyst. The present invention also relates to the use of said method as an intermediate step for preparing a compound inhibiting interleukin-1 beta converting enzyme (ICE).;/RTI ;/RTI