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Compositions containing local anesthesia for topical application which have an improved skin permeation rate
Compositions containing local anesthesia for topical application which have an improved skin permeation rate
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机译:含有局部麻醉的局部使用的组合物,具有改善的皮肤渗透率
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摘要
PURPOSE: A composition for topical application is provided which composition contains local anesthesia as an active ingredient and a pyrrolidine derivative as a skin permeation enhancer to improve skin permeation rate. CONSTITUTION: The composition for topical application contains: 0.2-20 wt.% of local anesthesia, as an active ingredient and 5-30 wt.% of pyrrolidine derivative, as a skin permeation enhancer. It further contains 5-50 wt.% of solvent and 0.5-25 wt.% of thickener. Also, it contains pharmaceutically acceptable additives such as moisturizing agents, pigments, preservatives, stabilizing agents, buffer, pH regulating agents and the like.
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