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Bioactive and biocompatible conjugates with magnetic properties and process for their preparation

机译:具有磁性的生物活性和生物相容性缀合物及其制备方法

摘要

The present invention relates to bioactive and biocompatible conjugates with magnetic properties and process for their preparation. Dollars a of the invention is the problem of providing a preparation of magnetically separable conjugates with a high bio - activity and bio - compatibility to enable. Dollars a according to the invention, this is achieved by magnetically separable, bioactive and biocompatible conjugates are produced from network structures with superparamagnetic or ferromagnetic properties, the partially of biomolecules and / or cells which are provided, where appropriate, with the anchor groups and one or more of channels perforated, crosslinked layers, which are partly made of magnetic iron oxides or mixed oxides of the formula meo x fe 2 o φ φ φ φ 3, wherein me divalent metal ions such as fe, ba, sr, mn, zn or co and fe φ 2 φ o φ 3 φ gamma - fe φ 2 φ o φ 3 φ or magnetic pure metals, such as cobalt and iron, by which the biomolecules and / or cells are biochemically can be achieved are constructed.
机译:本发明涉及具有磁性的生物活性和生物相容性缀合物及其制备方法。本发明的问题是提供一种制备具有高生物活性和生物相容性的可磁分离的缀合物的问题。根据本发明,这是通过具有超顺磁性或铁磁性性质的网络结构,部分生物分子和/或细胞(在适当情况下具有锚定基团和一个或多个)提供的可磁分离的,具有生物活性和生物相容性的缀合物来实现的。一个或多个通道穿孔的交联层,这些通道部分由式meo x fe 2 oφφφ3的磁性氧化铁或混合氧化物制成,其中二价金属离子如fe,ba,sr,mn,zn或者,可以构建能够实现生物分子和/或细胞生化的钴,铁,Fe 2 2φ3φ-Fe 2 2φ3φ或磁性纯金属。

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