Transfection using complex of plasmid, peptide and lipid, are useful in medicine, where the peptide comprises oligolysine sequence

摘要

Transfection using a complex (A) comprises plasmid DNA (I), a synthetic peptide (II) and a lipid (III). Independent claims are also included for: (a) cyclic peptide K16-CYC; (b) peptide K16-VprN; and (c) peptide K16-mVprN -VKLKVYPLKKKRKP- CK16 (K16-CYC) K16-GGGCNEWTLELLEELKNEAVRHF (K16-VprN) K16-GGGNEATLELLPELKNPAVRHF (K16-mVprN).