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Method for designing zinc finger class DNA binding protein
Method for designing zinc finger class DNA binding protein
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机译:锌指类DNA结合蛋白的设计方法
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摘要
The invention is directed to the design of DNA-binding proteins (DBP's) with capabilities of binding to any predetermined target double-stranded DNA sequence. Disclosed are the rules for design of the proteins; an algorithm for screening for the optimal DBP's; a computer system employing the rules and the algorithm; general formulae encompassing the proteins; and methods of use of the proteins.
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