New ionization method for mass spectrometry - Liquid chromatography: atmospheric pressure photoionization (APPI)

摘要

(57) analyzing apparatus and method for analyzing a test sample that is provided as a sample solution comprising the analyte and solvent summary is provided. Independently, or dopants, are given as the solvent of the sample solution. For example in the atomiser, is atomized, the sample solution is vaporized solvent. In order to ionize the dopant, in a region is at atmospheric pressure, the sample stream is irradiated with light in the gas state gasified in atomized droplets or liquid state, after the formation of droplets or mist liquid state, the atomization before . Then, by continuous collisions between the analyte and dopant ionization, directly or indirectly, the ionization of the analyte occurs. For mass spectrometry, the analyte ions are passed through the mass analyzer from the atmospheric pressure ionization region. This approach was found to give an ionization was intensified considerably for some materials in comparison with atmospheric pressure chemical ionization.