METHOD FOR CURING PAIN

摘要

PPROBLEM TO BE SOLVED: To provide a pain curing method. PSOLUTION: The pain curing method comprises the administration of a pharmaceutical composition containing an effective amount of a P2X receptor antagonist. The method is useful for mitigating various pains such as traumatic pain, neuropathic pain, visceralgia and disease-relating pain. The especially useful P2X receptor antagonist for the method is a mononucleoside- polyphosphate derivative of general formula I or a dinucleoside-polyphosphate derivative. The compound can be used singly for the treatment of pain or used in combination with other treating agent or an auxiliary treatment generally used for the treatment of pain to improve the pain mediating effect on the treating subject necessitating the pain-curing treatment. PCOPYRIGHT: (C)2003,JPO