PHARMACEUTICAL COMPOSITION, METHOD FOR ALLEVIATING TOBACCO-SMOKING WITHDRAWAL SYMPTOM IN PATIENT REFRAINING FROM SMOKING, AND KIT FOR ALLEVIATING TOBACCO- SMOKING WITHDRAWAL SYMPTOM IN PATIENT

摘要

PPROBLEM TO BE SOLVED: To provide a pharmaceutical composition for alleviating tobacco- smoking withdrawal symptom in a smoker. PSOLUTION: This kit for alleviating the tobacco-smoking withdrawal symptom in a patient comprises (a) a therapeutically effective amount of nicotine, at least one active nicotine metabolite, a combination of the nicotine and the active nicotine metabolite, or an azapirone, or a pharmaceutically acceptable salt thereof, (b) a transdermal delivery system consisting essentially of a bupropion base in a therapeutically effective amount, and (c) a packaging material surrounding (a) and (b). PCOPYRIGHT: (C)2003,JPO