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Isolation, characterization, cloning and use of a mushroom lectin
Isolation, characterization, cloning and use of a mushroom lectin
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机译:蘑菇凝集素的分离,鉴定,克隆和使用
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摘要
The isolation, characterization, cloning and expression of the lectin (agglutinin) from Marasmius oreades (MOA) is described. MOA displays unique carbohydrate binding properties, including blood group B-specific agglutination and preferential binding to Gal1,3Gal-containing sugar epitopes, including but not limited to Gal1,3Gal1,4GlcNAc. MOA is contemplated as an affinity reagent, a therapeutic in the treatment of antibiotic-induced diarrhea and the field of xenotransplantation. MOA may also serve as a diagnostic reagent, e.g. for malaria.
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