首页> 外国专利> Use of compounds of fatty acids of up to 22 carbon atoms and their derivatives to prepare drugs and / or reagents analu00ecticos with synergistic action and insulinomimu00e9tica and / or activating phosphorylation ofProteu00ecnas and / or regulator of the degree of proteu00ecnas and / or combat conditions associated with hyperglycemia and insulin deficiency or resistance to insulin action; composition with insulinomimu00e9tica and / or ATIVadora phosphorylation of proteu00ecnas and / or combat conditions associated with hyperglycemia and insulin deficiency or resistance to insulin on the basis of the compounds defined and method of application of the f.u00e1rmacos prepared on the basis of the compounds defined in combating conditions associated with hyperglycemia and insulin deficiency or resistance to insulin.

Use of compounds of fatty acids of up to 22 carbon atoms and their derivatives to prepare drugs and / or reagents analu00ecticos with synergistic action and insulinomimu00e9tica and / or activating phosphorylation ofProteu00ecnas and / or regulator of the degree of proteu00ecnas and / or combat conditions associated with hyperglycemia and insulin deficiency or resistance to insulin action; composition with insulinomimu00e9tica and / or ATIVadora phosphorylation of proteu00ecnas and / or combat conditions associated with hyperglycemia and insulin deficiency or resistance to insulin on the basis of the compounds defined and method of application of the f.u00e1rmacos prepared on the basis of the compounds defined in combating conditions associated with hyperglycemia and insulin deficiency or resistance to insulin.

机译:使用不超过22个碳原子的脂肪酸化合物及其衍生物制备具有协同作用的药物和/或肛肠药物,胰岛素和/或激活蛋白的磷酸化和/或程度调节剂蛋白质和/或与高血糖,胰岛素缺乏或对胰岛素作用的抵抗有关的疾病;根据所定义的化合物和应用该方法制备的胰岛素的组合物,其具有胰岛素类似物和/或ATIVadora引起蛋白蛋白的磷酸化和/或与高血糖和胰岛素缺乏或对胰岛素抵抗有关的疾病在对抗与高血糖和胰岛素缺乏或对胰岛素抵抗有关的疾病中定义的化合物的基础。

摘要

Use of compounds of fatty acids of up to 22 carbon atoms and their derivatives to prepare drugs and / or reagents analu00ecticos with synergistic action and insulinomimu00e9tica and / or activating phosphorylation ofProteu00ecnas and / or regulator of the degree of proteu00ecnas and / or combat conditions associated with hyperglycemia and insulin deficiency or resistance to insulin action; composition with insulinomimu00e9tica and / or at.Ivadora phosphorylation of proteu00ecnas and / or combat conditions associated with hyperglycemia and insulin deficiency or resistance to insulin on the basis of the compounds defined and method of application of theDrugs prepared on the basis of the compounds defined in combating conditions associated with hyperglycemia and insulin deficiency or resistance to insulin.It is the invention of the use of compounds of fatty acids of up to 22 carbon atoms and their derivatives for preparing medicines and analytical reagents with synergistic action and insulinomimu00e9tica and / or activator DAnd phosphorylation of proteins and / or regulatory protein level and / or combat conditions associated with hyperglycemia and insulin deficiency or resistance to insulin.Also refers,The composition with the action insulinomimu00e9tica and / or activating phosphorylation of proteins and / or combat conditions associated with hyperglycemia and insulin deficiency or resistance to insulin on the basis of theCompounds defined,As well as the application method of drugs and analytical reagents prepared on the basis of the compounds defined in combating conditions associated with hyperglycemia and insulin deficiency or resistu00eanThe CIA to insulin.The invention is situated in the fields of Medicine (human and veterinary) and biochemistry.Aiming at the use of new derivatives of fatty acids to prepare drugs for the prevention and treatment of diabetes melittus, and in particular,In the prevention and treatment of hyperglycaemia in diabetic patients, as well as research in vitro phosphorylation and cytoplasmic protein synthesis and activation or inhibition of phosphatases.The compounds based on fatty acids and their derivatives used in the invention have up to 22 carbon atoms and may be saturated or unsaturated chain.
机译:使用不超过22个碳原子的脂肪酸化合物及其衍生物制备具有协同作用的药物和/或肛肠药物,胰岛素和/或激活蛋白的磷酸化和/或程度调节剂蛋白质和/或与高血糖和胰岛素缺乏或对胰岛素作用的抵抗有关的疾病;在定义的化合物的基础上和在此基础上制备的药物的使用基础上,组成具有胰岛素类似物和/或at./或at.ipatora蛋白磷酸化和/或与高血糖,胰岛素缺乏或对胰岛素抵抗有关的疾病在对抗与高血糖和胰岛素缺乏或对胰岛素抵抗有关的疾病中定义的化合物。本发明的发明是使用多达22个碳原子的脂肪酸化合物及其衍生物制备具有协同作用和胰岛素类似物的药物和分析试剂和/或活化剂D和蛋白质的磷酸化和/或调节蛋白水平和/或与高血糖和胰岛素缺乏或对胰岛素抵抗有关的疾病。也指具有胰岛素样作用和//或作用的组合物激活蛋白质的磷酸化和/或对抗与高血糖有关的疾病根据定义的化合物确定胰岛素缺乏症或对胰岛素的抵抗力,以及根据在与高血糖和胰岛素缺乏症或胰岛素抵抗相关的CIA条件下抵抗疾病的条件下定义的化合物制备的药物和分析试剂的应用方法。本发明位于医学(人类和兽医学)和生物化学领域。旨在使用脂肪酸的新衍生物来制备用于预防和治疗糖尿病的药物,特别是用于预防和治疗糖尿病的高血糖症。糖尿病患者,以及研究体外磷酸化和胞质蛋白合成以及磷酸酶的活化或抑制。本发明中使用的基于脂肪酸的化合物及其衍生物具有至多22个碳原子,并且可以是饱和或不饱和链。

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