首页> 外国专利> USE OF PARATHYROIDE HORMONE CONSISTING OF AMINOACID SEQUENCE 1-34 OF HUMAN PARATHYROID HORMONE FOR REDUCING THE RISK OF BOTH VERTEBRAL AND NON VERTEBRAL BONE FRACTURE

USE OF PARATHYROIDE HORMONE CONSISTING OF AMINOACID SEQUENCE 1-34 OF HUMAN PARATHYROID HORMONE FOR REDUCING THE RISK OF BOTH VERTEBRAL AND NON VERTEBRAL BONE FRACTURE

机译:利用人甲状旁腺激素氨基酸序列1-34的甲状旁腺激素来降低椎骨和非椎骨骨折的风险

摘要

The invention relates to a method for increasing the toughness and/or stiffness of bone and/or reducing the likelihood and/or severity of bone fracture by administering a parathyroid hormone. The method can be employed to increase toughness or stiffness of bone at a site of a potential or actual trauma, such as the hip or spine of a person at risk of or suffering from osteoporosis. The method of the invention can reduce the incidence of vertebral fracture, reduce the incidence of multiple vertebral fractures, reduce the severity of vertebral fracture, and/or reduce the incidence of non-vertebral fracture.
机译:本发明涉及一种通过施用甲状旁腺激素来增加骨的韧性和/或刚度和/或降低骨折的可能性和/或严重性的方法。可以采用该方法来增加潜在或实际创伤部位(例如处于患骨质疏松症风险或遭受骨质疏松症的人的臀部或脊椎)的骨骼的韧性或刚度。本发明的方法可以减少椎骨骨折的发生率,减少多发性椎骨骨折的发生率,降低椎骨骨折的严重性,和/或减少非椎骨骨折的发生率。

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