Device for the generation of bone tissue, comprising a biodegradable thermoplastic copolyester and cultured from cells.

摘要

The invention relates to a device for bone regeneration, comprising a support material copolyester THERMOPLASTIC FORMED BY TARGETED FOR BONE UNION, osteoconductive, BIOACTIVE AND CELLS CULTURED osteoprogenitoras U osteogenic cells, especially Hos. The copolyester is essentially formed by a multiplicity of ester units CHAIN ​​LONG REPETITIVE, AND UNITS OF ESTER CHAIN ​​SHORT, SO THE UNITS OF ESTER LONG CHAIN ​​CONSTITUTE 35 to 80% by weight of the copolyester, AND ARE REPRESENTED BY THE FORMULA: AND CHAINS OF ESTER CORTAS are represented by the formula wherein L is a divalent group STAYING after removing the terminal hydroxyl groups FROM A poly (oxyalkylene) glycol having an average molecular weight between 300 and 3000 ; R is a divalent group remaining after carboxyl groups REMOVING FROM A dicarboxylic acid AN AVERAGE lower molecular weight 300; Q ESUN GROUP alkylene 1-6 carbon atoms and / or a group phenylene or cyclohexylene; E is an alkylene group of 2-6 carbon atoms.