REACTIVE COMPOSITION FOR HEMOGLOBIN CONTAINING CYANIDE AND A PROCEDURE THAT PROVIDES ACCEPTABLE ACCURACY AND ACCURACY WITHOUT INTERFERENCE FOR WHITE BALLOONS IN AUTOMATIC HEMATOLOGICAL ANALYZERS.

摘要

THE INVENTION REFERS TO THE COMPOSITION OF AN IMPROVED STABLE REAGENT AND TO A METHOD OF DETERMINATION OF HEMOGLOBIN (HB) THAT USES WHOLE BLOOD SAMPLES AND AUTOMATED HEMATOLOGICAL ANALYZERS, AS FOR EXAMPLE THE INSTRUMENT TM COMMERCIAL SERIES PATENT. THE HB DETERMINATION REAGENT INCLUDES AN INORGANIC CYANIDE SALT, AT LEAST ONE TENSIOACTIVE AND A BASE AND HAS A FINAL PH OF BETWEEN 10.0 AND 11.2, PREFERIBLY BETWEEN 10.4 AND 11.2 OR LOWER AND MORE PREFERIBLY BETWEEN 10.8 AND 11.2 OR LOWER. THIS REAGENT IS INTENDED TO BE USED AS A REPORT FOR THE DETERMINATION OF UNIVERSAL HB FOR ALL INSTRUMENTS OF THE CITED SERIES AND ALLOWS TO OBTAIN PRECISIVE RESULTS WITHOUT INTERFERING THE PRESENCE OF A GREAT AMOUNT OF WHITE BALLOONS, ESPECIALLY IN THE CASE OF A WOMAN WITHOUT VARIATION OF THE RESULTS OBTAINED FROM ONE SYSTEM TO ANOTHER.