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USE OF INSECT CELL MEMBRANE TRANSPORTERS AS NOVEL TARGET SITES FOR INSECTICIDES
USE OF INSECT CELL MEMBRANE TRANSPORTERS AS NOVEL TARGET SITES FOR INSECTICIDES
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机译:使用昆虫细胞膜转运蛋白作为杀虫剂的新靶标
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摘要
The present invention discloses the existence of novel insect transporters that can be used as targets for screening of new insecticides. This invention provides nucleic acids which encode the following insect cell membrane transporters: acetylcholine transporters, serotonin transporters, proline transporters, glutamate transporters, neurotransmitter transporters encoded by the inebriated gene, orphan transporters, GABA transporters, and LAT transporters. The invention also provides the polypeptides, cells expressing the polypeptides, and methods of using the nucleic acids and polypeptides to identify compounds which bind to or modulate the activity of the above-listed insect cell membrane transporters.
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