PURIFIED MATERIAL HAVING SIZE AND GROWTH INHIBITORY EFFECTS ON CELLS AND TISSUES

摘要

A method of purifying a material ("Micrin") with the ability to reduce cell, tissue and organ size, mass and growth, comprises collection of ovarian follicular fluid from a mammal and at least partially purifying said material. Another method for purifying Micrin comprises collection of blood from a mammal and at least partially purifying said material, wherein during the collection a chelating agent is mixed with the collecting blood. Micrin or Micrin blockade has utility in the treatment of hyperplastic disorders, e.g. cancer, and also for preventing and treating a tissue-deficit disorder, or for controlling the shape, appearance or density of cells and tissues.