The present invention relates to indicating a potent cell modulating activity, including proliferation and angiogenesis inhibitory effect relates to a compound of formula I.; Formula I; Wherein; R 1 represents a hydrogen atom or an O- protecting group;; R 2 is hydroxyl, lower alkoxy, carboxaldehyde, lower alk-1-enyl or hydroxy- or lower alkoxy-represents a substituted lower alkyl group;; R 3 represents a methyl group in the α- or β- configuration;; X is a C 1-3 alkylene group, or denotes a valence bond;; Y is carboxamide, aldehyde group or the formula -C (R 4) (R 5 ) OR 1 ( wherein, R 1 is as defined above, R 4 and R 5 may be the same or different and are each a hydrogen atom, alkyl, alkenyl and the alkynyl group is selected from R 4, and the total carbon content of R 5 does not exceed three atoms) groups are shown in, with the proviso that R 4 and R 5 are both hydrogen or X is a valence bond;; The dotted line is optionally a double bond 16 (17) - it indicates that may be present in the position.
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