Direct fluorination of (in)organic substrate, for producing electrophilic fluorinating reagent, e.g. alkyl or acyl hypofluorite or N-fluoro-amide, -imide, -lactam, -bis(sulfonyl)amine or -sultam, uses silica particles as inert medium

摘要

In fluorination of (in)organic substrate(s) using fluorine (F2) in the presence of at least one inert reaction medium, by passing F2 through and/or over a mixture of the substrate and medium, particles containing silica (SiO2) are used as medium. An Independent claim is also included for use of particles containing SiO2 as inert reaction medium in this process.