MODULATION OF EXPRESSION OF TH1 TYPE /TH2 TYPE CYTOKININ BY RIBAVIRIN AND RIBAVIRIN ANALOGUE IN ACTIVATED T LYMPHOCYTE

摘要

PPROBLEM TO BE SOLVED: To provide a use of ribavirin in the production of a medicine for treating diseases, useful as an immuno-modulation treating agent. PSOLUTION: The ribavirin is administered to a patient within the range of a dosage effective for the modulation of expression of a lymphokine in an activated T cell. Especially, the ribavirin is used for inhibiting the Th2-mediated T cell response and accelerating the Th1-mediated T cell response. In other aspect of this invention, 1 kind of the ribavirin analogs are administered to a patient within the range of the total dosage effective for the modulation of expression of the lymphokine in the activated T cell. These ribavirin analogs can be used for inhibiting or accelerating the Th1 or Th2-mediated T cell response. PCOPYRIGHT: (C)2004,JPO