首页>
外国专利>
Human fgf23 protein mutants lowering blood phosphorus level
Human fgf23 protein mutants lowering blood phosphorus level
展开▼
机译:人类fgf23蛋白突变体降低血磷水平
展开▼
页面导航
摘要
著录项
相似文献
摘要
A full-length cDNA encoding the human FGF23 protein was isolated, and mutants having a single amino acid substitution in the cDNA were constructed using the mutagenesis method. These mutants had the effect of decreasing the phosphorus level in the blood when expressed in vivo. These mutants and the DNAs encoding them are expected to be useful as therapeutic agents, or employed for gene therapy against hyperphosphatemia.
展开▼