Chemical antibodies, humanized and simple FV short chain segments, are recognized by human C2. Diagnosis and treatment of colonic tumor

摘要

The invention relates to obtaining a new recombinant antibody from murino IOR C5 antibody produced by hibridoma deposited with ECCC 97061101 according to Budapest Treaty. These recombinant antibodies are obtained by recombinant DNA technology, which is characterized by the recognition of antigens symmetrical to iorc2. Recombinant antibodies are special, chemotherapeutic antibodies,Human antibodies and simple chain Fv fragments Cosmetic antibodies contain the variable domain of Murina immunoglobulin and the constant domain of human immunoglobulin. Human antibodies contain a constant region of human immunoglobulin, which has been specially changed in Marcos region and these regions, which may lead to the antigen location of T. fragm cells.Nto FV contains the variable domain of immunoglobulin Murina. The present invention also relates to the diagnosis and treatment of colon tumor by using the recombinant antibody extracted from the murino antibody of IOR C5 type.Your movement and recitation To this end, the invention provides an ingredient which contains a smaller single clone antibody, recognizes the iorc2 antigen and a weak ligament, namely MD and S2 + reductant, so as to radiolabel the antibody with Tc-99m, Re-186, r-188 and similar materials, It is helpful for the diagnosis of colon, metastasis and back tumor through immunomotor and radioimmunotherapy.