association of an antagonist of histamine h1 receptors and an antagonist of histamine h4 receptors selective, and composition containing them.

摘要

the invention provides a combination of (a) an antagonist of histamine h1 receptors, and (b) an antagonist that is at least 10 times more selective histamine h4 receptor for the histamine h3 receptor in the. it is also a pharmaceutical composition containing them.application: the use of the combination or composition for the treatment of various diseases, such as allergic rhinitis or asthma.