首页> 外国专利> DERIVATIVES OF HETEROCICLOALQUIL-BENZO-CICLOBUTANO AND HETEROARIL-BENZO-CICLOBUTANO AND ITS USE AS INHIBITORS OF RECAPTURE OF SEROTONINE AND NORADRENALINE.

DERIVATIVES OF HETEROCICLOALQUIL-BENZO-CICLOBUTANO AND HETEROARIL-BENZO-CICLOBUTANO AND ITS USE AS INHIBITORS OF RECAPTURE OF SEROTONINE AND NORADRENALINE.

机译:异环己基-苯并-环丁酮和异芳基-苯并-环丁酮的衍生物及其用作5-羟色胺和去甲肾上腺素夺回抑制剂。

摘要

Compounds of ** formula ** in which a single bond or a double bond, n represents R1, R2, identical or different, independent of each other, represent a group chosen from a hydrogen atom, a (C1-C6) alkyl group Linear or branched 2, 3-dihydro-1, 4-benzodioxin-2-ylmethyl X represents a group selected from ¿CH = CH-, oxygen atom, group S (O) m in which m is an integer comprised between 0 and 2 included, and NR3 in which R3 represents a group selected from a hydrogen atom, a linear or branched (C1-C6) alkyl, aryl, aryl, linear or branched (C1-C6) alkyl, cycloalkyl group, linear or branched cycloalkyl (C1-C6) alkyl, linear or branched (C2-C6) alkenyl, and linear or branched (C2-C6) alkynyl, Y represents a CH or CH2 group depending on whether it represents a double bond or a single bond , or it can take the supplementary definition of oxygen atom when X represents an oxygen atom, T represents a cyclopentyl or cyclohexyl group, its s optical isomers as well as their addition salts to an acid or a pharmaceutically acceptable base.
机译:式**的化合物,其中单键或双键,n表示R1,R2,彼此相同或不同,彼此独立,表示选自氢原子的基团,(C1-C6)烷基或支链的2,3-二氢-1,4-苯并二恶英-2-基甲基X表示选自?CH = CH-的基团,氧原子,S(O)m基团,其中m是0到2之间的整数以及其中R3代表选自氢原子的基团的NR3,直链或支链(C1-C6)烷基,芳基,芳基,直链或支链(C1-C6)烷基,环烷基,直链或支链环烷基(C1- C 6)烷基,直链或支链(C 2 -C 6)烯基和直链或支链(C 2 -C 6)炔基,Y表示CH或CH 2基团,取决于它是表示双键还是单键,或者可以采用当X代表一个氧原子,T代表一个环戊基或环己基时,它的旋光异构体及其与酸o的加成盐的氧原子的补充定义r是药学上可接受的碱。

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