Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them

摘要

Novel C-13SUP2/SUP-COXRSUB1/SUB, C-17SUP2/SUP-COXRSUB2 /SUBand C-13SUP2/SUP-COXRSUB1/SUB, C-17SUP2/SUP-COXRSUB1 /SUBderivatives of chlorophyll and bacteriochlorophyll compounds are provided wherein X is O, S or N and RSUB1 /SUBand RSUB2/SUB, the same or different, may be an optionally substituted hydrocarbyl, amino acid, peptide, protein or saccharide radical. The compounds are for use in photodynamic therapy (PDT), for diagnosis of tumors, and for killing cells and infectious agents such as bacteria and virus, both in biological products and in living tissues.