Expression contructs using Lactobacillus delbrueckii subsp. lactis lac repressor protein and its lac repressor binding site, microorganisms and methods thereof

摘要

A DNA sequence suitable for the controlled transcription and/or expression of a variety of different genes in bacteria, preferably gram positive bacteria is provided. In particular, the DNA sequence includes the promoter and the gene coding for the lac repressor of the lac operon of Lactobacillus delbrueckii with a DNA sequence coding for a gene product of interest being arranged inbetween.