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Drugs for Perioperative Therapy of two phases of Solid Tumors

机译:实体瘤两个阶段的围手术期治疗药物

摘要

1. A drug for preoperative treatment of two-stage solid tumors was developed by using a preparation with tumor specific drugs and another preparation with anticancer activity and close relationship with the former preparation. This means that it is necessary to better determine the location of its anti-cancer activities, reduce the number of stages of use, and possibly reduce the dose of anti-cancer, thus reducing the lateral impact, but at the same time maintaining its effectiveness. D. Claim 2: Employment under claim 1Agents labeled as tumor specific contain one or more specific antibodies to tumor related antigens. 13. Claim 3: used according to claim 2, which is characterized in that the antibody or antibody in the drug is a biotoxin and is combined with an avidin compound, which is a biotoxin compound containing an anticancer agent. Claim 4 employment provided under claim 2,It is characterized in that the antibody in the drug is avidina, and is combined with a biological group compound containing an anticancer agent. Claim 6: any employment under claims 2 to 5, which is characterized by antibody resistance. 19. Claim 8: used in accordance with any of the above requirements, characterized by the fact that the anticancer agent is selected from a group consisting of radioisotopes, chemokinetic agents, toxins and anticancer cells. D. Claim 9: Employment in accordance with claim 8,It is characterized by the selection of this radioisomer from fe-52, mn-52m, co-55, Cu-64, Ga-67, Ga-68, Tc-99m, In-111, I-123, I-125, I-131, P-32, sc-47, cu-67, Y-90, pd-109, ag-111, I-131, pm-149, Re-186, Re-188, at-211, pb-212, bi-212, lu-177 and other groups. Claim 25: a two-stage concurrent system and / or local and near functional antiretroviral therapy package, comprising a separate set of containers, the first containing specific biological antigen antibodies related to tumors or antibody mixtures, The second container contains an avidin compound,The third package contains a biotoxin compound containing an anticancer agent, while the fourth package contains biological albumin.
机译:通过使用一种具有肿瘤特异性药物的制剂和另一种具有抗癌活性并与前一种制剂有密切关系的制剂,开发了一种用于术前治疗两阶段实体瘤的药物。这意味着有必要更好地确定其抗癌活性的位置,减少使用阶段的数量,并可能减少抗癌的剂量,从而减少横向影响,但同时保持其有效性。 。 D.权利要求2:根据权利要求1的雇用,标记为肿瘤特异性的代理包含一种或多种针对肿瘤相关抗原的特异性抗体。 13.根据权利要求2所述的用途,其特征在于,所述药物中的一种或多种抗体是生物毒素并且与抗生物素蛋白化合物结合,所述抗生物素蛋白化合物是含有抗癌剂的生物毒素化合物。根据权利要求2提供的权利要求4,其特征在于,药物中的抗体是抗生物素蛋白,并与含有抗癌剂的生物基化合物结合。权利要求6:根据权利要求2至5的任何雇佣,其特征在于抗体抗性。 19.权利要求8:根据上述要求中的任一项使用,其特征在于所述抗癌剂选自放射性同位素,化学动力学剂,毒素和抗癌细胞。 D.权利要求9:根据权利要求8所述的就业,其特征在于,该放射性异构体选自fe-52,mn-52m,co-55,Cu-64,Ga-67,Ga-68,Tc-99m, In-111,I-123,I-125,I-131,P-32,sc-47,cu-67,Y-90,pd-109,ag-111,I-131,pm-149,Re- 186,Re-188,at-211,pb-212,bi-212,lu-177和其他群组。 25.权利要求25的两阶段并发系统和/或局部和接近功能的抗逆转录病毒疗法包装,包括单独的容器组,第一容器包含与肿瘤或抗体混合物有关的特定生物抗原抗体,第二容器包含抗生物素蛋白化合物,第三包装包含含有抗癌剂的生物毒素化合物,而第四包装包含生物白蛋白。

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