Factor vii polypeptide, factor vii derivative, composition, pharmaceutical composition, polynucleotide construction, eukaryotic host cell, transgenic animal, transgenic plant, and methods for producing factor vii polypeptide and a factor vii derivative, use of a derivative of vii, methods for treating bleeding episodes or bleeding disorders in a patient or for enhancing the normal hemostatic system and inhibiting thrombus formation in a patient

摘要

"Factor VII polypeptide, Factor VII derivative, COMPOSITION, PHARMACEUTICAL COMPOSITION, POLYNUCLEOTIDE CONSTRUCTION, EUCHARIOTIC HOST, TRANSGENIC ANIMAL PLANT, FG7 AND A TRANSGENTIDOUS PLANT FACTOR VII DERIVATIVE, METHODS FOR TREATMENT OF HEMORRAGY EPISODES OR HEMORRAGY DISTURBANCES IN A PATIENT OR FOR THE INTENSIFICATION OF THE NORMAL HEMOSTATIC SYSTEM AND TO INHIBIT THE FORM OF BUMP TRAINING ". The present invention relates to novel human coagulation Factor VII polypeptides, Factor VII derivatives as well as polynucleotide constructs encoding such polypeptides, vectors and host cells comprising and expressing the polynucleotide, pharmaceutical compositions, uses and methods. of treatment.