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The use of a variant of polipeptu00ecdeo interferon beta (IFNb), and methods for treating or preventing stroke or cerebrovascular accident (CVA) and ischemic attack in a primate
The use of a variant of polipeptu00ecdeo interferon beta (IFNb), and methods for treating or preventing stroke or cerebrovascular accident (CVA) and ischemic attack in a primate
The use of a variant of polipeptu00ecdeo interferon beta (IFNb), and methods for treating or preventing stroke or cerebrovascular accident (CVA) and ischemic attack in a primate. The present invention relates to the use of polypeptides similar to interferon beta for the treatment of stroke or transient ischemic attack in a primate, preferably on a human being.More particularly, the polypeptides similar to interferon beta differs from the sequ00b3u00eancia IFNb amino acid of human wild type (SEQ ID No: 2) in which at least one glycosylation site.Preferably at least one place of N - glycosylation in vivo was u00edntroduzido. Optionally the polypeptides similar to pegylated interferon beta are
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机译:lip肽干扰素β(IFNb)变体的用途,以及在灵长类动物中治疗或预防中风或脑血管意外(CVA)和缺血性发作的方法。本发明涉及类似于干扰素β的多肽在灵长类动物中,优选对人的中风或短暂性脑缺血发作的治疗中的用途。更具体地,类似于干扰素β的多肽不同于seq u00b3 u00eancia人野生型的IFNb氨基酸(SEQ ID No:2),其中至少一个糖基化位点。体内至少N-糖基化的至少一个位置是edrodroduzido。任选地,类似于聚乙二醇化干扰素β的多肽是
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